Warren Marsh’s journey in and around Phoenix-City in REPLACED is a dangerous one full of hazardous obstacles and formidable enemies. While having enough firepower to contend with those enemies is a definite priority, survivability is just as important. Thankfully, the game provides a variety of upgrades to help even the odds.

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Some of those upgrades include invaluable ones for your health gauge and the Med-Stim feature, which will help you last through the game’s most uphill battles. Better yet, finding them all gets you an achievement, so here’s where to find all Health and Med-Stim upgrades in REPLACED.

How Do Health and Med-Stim Upgrades Work in REPLACED?

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Health upgrades provide you with permanent boosts to your health gauge, which is indicated by a row of red hearts in the top-left corner of the screen. Each upgrade usually adds half a heart, and they’re technically referred to in-game as ‘Genetic Profile’ upgrades.

Meanwhile, Med-Stim upgrades provide boosts to the Med-Stims you use during combat to replenish your health gauge. They can increase their overall effectiveness and also increase the number of Med-Stims you can use during a fight. They’re technically referred to with in-game as terms like ‘Immune Modulator’ or ‘Rechargeable Ampoule’.

Health and Med-Stim Upgrades are vital for surviving combat challenges at every turn in REPLACED. Your vitality doesn’t necessarily matter as much for environmental obstacles in platform sequences, as missing a jump or landing in a hazardous area almost always means death and a checkpoint reset. However, as the game’s combat encounters get more difficult, having as much health and endurance as possible is an absolute necessity.

If you collect all Health and Med-Stim upgrades in the game, you’ll unlock the ‘My Body Is a Machine’ achievement.

All Health and Med-Stim Upgrade Locations in REPLACED

Below is a comprehensive list of all Health and Med-Stim upgrades in REPLACED, including where or how to get them in each chapter.

Chapter 1

Health Upgrade 1 – Outside of Diner

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Genetic Profile – Health increased

The game’s first Health upgrade is on the ground just outside the entrance of an abandoned diner (look for the large sign in the background) during the Termite stealth sequence.

Chapter 2

Med-Stim Upgrade – Doctor Quest Reward

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Rechargeable Ampoule 1 – Med-Stims amount increased

This upgrade is provided as a reward for completing the Doctor’s sidequest available during this specific chapter.

Med-Stim Upgrade – Donor Rush Arcade Game Reward

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Immune Modulator – Now Med-Stims are used much faster

This upgrade is provided as a reward for beating Susan’s high score in the Donor Rush arcade mini-game after it’s repaired.

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Health Upgrade – My Only Sunshine Quest Reward

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Genetic Profile 2 – Health increased

This upgrade is provided as a reward for completing David’s side quest to fix his telescope.

Chapter 3

Health Upgrade – Subway Station Office

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Genetic Profile 4 – Health increased

This upgrade is found inside a hidden office room in the subway section of Chapter 3. Just after you first get and use the Pickaxe, keep running to the right on the elevated platform until you reach the edge. Instead of proceeding, watch for the button prompt to turn and run towards the open door in the background, and then run left into the office area. Keep going left until you reach the end, where you can pick up the upgrade.

Health Upgrade – Subway Platform Room

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Genetic Profile 3 – Health increased

This upgrade is located further in the subway zone, specifically in the section with the multiple climbing obstacles in front of the ‘Prospero Facility’ platform. Keep running to the right until you go through an open door into a hidden room. Keep moving right until you get the ‘Scan’ prompt and select it to get the upgrade.

Chapter 4

Health Upgrade – Old Man Quest Reward

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Genetic Profile 5 – Health increased

This upgrade is provided as the reward for completing the Old Man’s side quest at the Hospital. See our Family Reunion Quest Guide for details on how to complete it.

Med-Stim Upgrade – Edward Quest Reward

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Rechargeable Ampoule 2 – Med-Stims amount increased

This upgrade is provided as a reward for completing Edward’s side quest, which starts inside Western Station. Once you examine the graffiti on the west side of the station building, the upgrade will unlock for you.

Chapter 5

Health Upgrade – Lower Level of Subway Station

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Genetic Profile 6 – Health increased

This upgrade is found on the ground beneath an elevated platform with an abandoned train car.

Chapter 6

Health Upgrade – Vent Beneath Server Room

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Genetic Profile 7 – Health increased

This upgrade is located in the massive server room section of the chapter. Make your way to the right across the room until there’s a gap in one of the server towers where you can drop down to where the floor panels have been opened. Drop all the way down and then crawl left through the narrow vent shaft until you find the upgrade to scan.

Chapter 7

Health Upgrade – Sandra Side Quest Reward

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Genetic Profile 9 – Health increased

This upgrade is provided as the main reward for completing Sandra’s side quest, which you can pick up inside the Western Station. After reuniting with her and the twin brothers, the upgrade will unlock.

Med-Stim Upgrade – Arcade Game Reward

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Adrenaline Injector – Restores a small amount of health after a fatal blow. Can be triggered once per combat.

This upgrade is given as the reward for beating all three arcade games at the arcade in the Western Station with the highest score. This will also give you the Old School achievement.

Chapter 8

Med-Stim Upgrade – Steam Vent Room Beneath City Streets

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Rechargeable Ampoule 3 – Med-Stims amount increased

This upgrade is found inside a small vent nook inside the ‘DEP 311’ room (in big letters on the wall) underneath the city streets. You’ll make your way down here while trying to hack into the Phoenix Saving and Loans queue system for the last sanitation worker. Push the steam cart all the way to the right against the wall and use your double jump to reach the small vent shaft.

Chapter 9

Health Upgrade – Tower Atrium Climbing Section

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Genetic Profile 10 – Health increased

After you defeat a group of enemies on the ground level of the Phoenix Lab tower atrium, you have to climb all the way up to reach the next section of the chapter. This upgrade is located on the balcony on the left side of the fourth (04) level. You’ll find it at the same time as the ‘Exquisite Menu’ collectible.

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Systems

PC-1

Xbox-1

Released

April 14, 2026

ESRB

Mature 17+ / Violence, Blood, Strong Language

Developer(s)

Sad Cat Studios

Publisher(s)

Coatsink, Thunderful Development

Number of Players

Single-player



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